Epitherapy and immune checkpoint blockade: using epigenetic reinvigoration of exhausted and dysfunctional T cells to reimburse immunotherapy response.

McGoverne, Isabella; Dunn, Jenny; Batham, Jacob; Tu, Wen Juan; Chrisp, Jeremy; Rao, Sudha

McGoverne, Isabella; Dunn, Jenny; Batham, Jacob; Tu, Wen Juan; Chrisp, Jeremy; Rao, Sudha.

Afiliación

McGoverne I; Melanie Swan Memorial Translational Centre, Faculty of Science and Technology, University of Canberra, Canberra, Australia.
Dunn J; Gene Regulation and Translational Medicine Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Batham J; Melanie Swan Memorial Translational Centre, Faculty of Science and Technology, University of Canberra, Canberra, Australia.
Tu WJ; Gene Regulation and Translational Medicine Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Chrisp J; EpiAxis Therapeutics, Brisbane, Australia.
Rao S; Gene Regulation and Translational Medicine Laboratory, Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, Australia. Sudha.rao@qimrberghofer.edu.au.

BMC Immunol ; 21(1): 22, 2020 04 21.

Article en En | MEDLINE | ID: mdl-32316916

Asunto(s)

Epigénesis Genética/inmunología; Inhibidores de Puntos de Control Inmunológico/inmunología; Linfocitos T/inmunología; Animales; Antígeno B7-H1/inmunología; Humanos; Inmunoterapia/métodos; Neoplasias/inmunología; Neoplasias/terapia

Palabras clave

Epigenetics; Immune system; Immunotherapy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T / Epigénesis Genética / Inhibidores de Puntos de Control Inmunológico Límite: Animals / Humans Idioma: En Revista: BMC Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Australia

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