Are Parallel Proliferation Pathways Redundant?

Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum

Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum.

Afiliación

Nussinov R; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: NussinoR@mail.nih.gov.
Tsai CJ; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
Jang H; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

Trends Biochem Sci ; 45(7): 554-563, 2020 07.

Article en En | MEDLINE | ID: mdl-32345469

Asunto(s)

Proliferación Celular/genética; Neoplasias/patología; Cromatina/metabolismo; Humanos; Neoplasias/genética; Transducción de Señal/genética

Palabras clave

K-Ras; cancer; chromatin accessibility; drug resistance; free energy landscape; isoforms; precision medicine initiative; signaling

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proliferación Celular / Neoplasias Límite: Humans Idioma: En Revista: Trends Biochem Sci Año: 2020 Tipo del documento: Article

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