Epidemiology of thrombosis in Canadian neonatal intensive care units.
J Perinatol
; 40(7): 1083-1090, 2020 07.
Article
en En
| MEDLINE
| ID: mdl-32385393
ABSTRACT
OBJECTIVE:
To assess the rate, location, risk factors, management, and outcomes of neonatal thrombosis (NT).DESIGN:
A retrospective study investigating infants admitted to NICUs in Canadian Neonatal Network between January 2014 and December 2016 and diagnosed with NT. Each infant with NT was matched with an infant without NT.RESULTS:
Of 39,971 infants, 587 (1.5%) were diagnosed with NT 440 (75%) venous, 112 (19%) arterial, 29 (5%) both. NT rate was 1.4% in full-term and 1.7% in preterm infants. Venous thrombi occurred most commonly in the portal vein and arterial thrombi in the cerebral artery. Conservative management and low molecular weight heparin were the most common treatment modalities. Hospital stay was longer (p < 0.001) in the NT patients, but mortality was similar.CONCLUSIONS:
NT was diagnosed in ~15/1000 NICU admissions and most commonly in the portal vein and cerebral arteries. Management varied based on the type and location of thrombi. Large multicenter trials are needed to address the best management strategies.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Trombosis
/
Unidades de Cuidado Intensivo Neonatal
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
/
Infant
/
Newborn
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Canadá