Oxidative Stress-Induced Axon Fragmentation Is a Consequence of Reduced Axonal Transport in Hereditary Spastic Paraplegia <i>SPAST</i> Patient Neurons.

Wali, Gautam; Liyanage, Erandhi; Blair, Nicholas F; Sutharsan, Ratneswary; Park, Jin-Sung; Mackay-Sim, Alan; Sue, Carolyn M

Oxidative Stress-Induced Axon Fragmentation Is a Consequence of Reduced Axonal Transport in Hereditary Spastic Paraplegia SPAST Patient Neurons.

Wali, Gautam; Liyanage, Erandhi; Blair, Nicholas F; Sutharsan, Ratneswary; Park, Jin-Sung; Mackay-Sim, Alan; Sue, Carolyn M.

Afiliación

Wali G; Department of Neurogenetics, Kolling Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia.
Liyanage E; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Blair NF; Department of Neurogenetics, Kolling Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia.
Sutharsan R; Department of Neurogenetics, Kolling Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia.
Park JS; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Mackay-Sim A; Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia.
Sue CM; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.

Front Neurosci ; 14: 401, 2020.

Article en En | MEDLINE | ID: mdl-32457567

Palabras clave

SPAST; axon degeneration; axon transport; epothilone D; hereditary spastic paraplegia; noscapine; peroxisomes

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Front Neurosci Año: 2020 Tipo del documento: Article País de afiliación: Australia

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Front Neurosci Año: 2020 Tipo del documento: Article País de afiliación: Australia