Reward Contributions to Serotonergic Functions.
Annu Rev Neurosci
; 43: 141-162, 2020 07 08.
Article
en En
| MEDLINE
| ID: mdl-32640931
ABSTRACT
The brain serotonin systems participate in numerous aspects of reward processing, although it remains elusive how exactly serotonin signals regulate neural computation and reward-related behavior. The application of optogenetics and imaging techniques during the last decade has provided many insights. Here, we review recent progress on the organization and physiology of the dorsal raphe serotonin neurons and the relationships between their activity and behavioral functions in the context of reward processing. We also discuss several interesting theories on serotonin's function and how these theories may be reconciled by the possibility that serotonin, acting in synergy with coreleased glutamate, tracks and calculates the so-called beneficialness of the current state to guide an animal's behavior in dynamic environments.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Recompensa
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Encéfalo
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Serotonina
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Neuronas
Límite:
Animals
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Humans
Idioma:
En
Revista:
Annu Rev Neurosci
Año:
2020
Tipo del documento:
Article