Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging.

Vijg, Jan; Dong, Xiao

Vijg, Jan; Dong, Xiao.

Afiliación

Vijg J; Department of Genetics, Albert Einstein College of Medicine, New York, NY 10461, USA; Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address: jan.vijg@einsteinmed.org.
Dong X; Department of Genetics, Albert Einstein College of Medicine, New York, NY 10461, USA.

Cell ; 182(1): 12-23, 2020 07 09.

Article en En | MEDLINE | ID: mdl-32649873

Asunto(s)

Envejecimiento/genética; Genoma; Mosaicismo; Mutación/genética; Células Clonales; Enfermedad/genética; Redes Reguladoras de Genes; Humanos

Palabras clave

age-related disease; aging; genome mosaicism; pathogenic effects; somatic DNA mutation; transcriptional noise

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Genoma / Mosaicismo / Mutación Límite: Humans Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article

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