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Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma.
Gillette, Michael A; Satpathy, Shankha; Cao, Song; Dhanasekaran, Saravana M; Vasaikar, Suhas V; Krug, Karsten; Petralia, Francesca; Li, Yize; Liang, Wen-Wei; Reva, Boris; Krek, Azra; Ji, Jiayi; Song, Xiaoyu; Liu, Wenke; Hong, Runyu; Yao, Lijun; Blumenberg, Lili; Savage, Sara R; Wendl, Michael C; Wen, Bo; Li, Kai; Tang, Lauren C; MacMullan, Melanie A; Avanessian, Shayan C; Kane, M Harry; Newton, Chelsea J; Cornwell, MacIntosh; Kothadia, Ramani B; Ma, Weiping; Yoo, Seungyeul; Mannan, Rahul; Vats, Pankaj; Kumar-Sinha, Chandan; Kawaler, Emily A; Omelchenko, Tatiana; Colaprico, Antonio; Geffen, Yifat; Maruvka, Yosef E; da Veiga Leprevost, Felipe; Wiznerowicz, Maciej; Gümüs, Zeynep H; Veluswamy, Rajwanth R; Hostetter, Galen; Heiman, David I; Wyczalkowski, Matthew A; Hiltke, Tara; Mesri, Mehdi; Kinsinger, Christopher R; Boja, Emily S; Omenn, Gilbert S.
Afiliación
  • Gillette MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, 02115, USA. Electronic address: gillette@broadinstitute.org.
  • Satpathy S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA. Electronic address: shankha@broadinstitue.org.
  • Cao S; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Dhanasekaran SM; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Vasaikar SV; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Krug K; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Petralia F; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Li Y; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Liang WW; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Reva B; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Krek A; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Ji J; Department of Population Health Science and Policy; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Song X; Department of Population Health Science and Policy; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Liu W; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.
  • Hong R; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.
  • Yao L; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Blumenberg L; Institute for Systems Genetics and Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.
  • Savage SR; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Wendl MC; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Wen B; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Li K; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Tang LC; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA.
  • MacMullan MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA; Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA, 90089, USA.
  • Avanessian SC; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Kane MH; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Newton CJ; Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
  • Cornwell M; Institute for Systems Genetics and Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.
  • Kothadia RB; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Ma W; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Yoo S; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Mannan R; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Vats P; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Kumar-Sinha C; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Kawaler EA; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.
  • Omelchenko T; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Colaprico A; Department of Public Health Sciences, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA.
  • Geffen Y; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Maruvka YE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • da Veiga Leprevost F; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Wiznerowicz M; Poznan University of Medical Sciences, Poznan, 61-701, Poland; International Institute for Molecular Oncology, Poznan, 60-203, Poland.
  • Gümüs ZH; Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Veluswamy RR; Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Hostetter G; Van Andel Research Institute, Grand Rapids, MI, 49503, USA.
  • Heiman DI; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA.
  • Wyczalkowski MA; Department of Medicine and Genetics, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Hiltke T; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Mesri M; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Kinsinger CR; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Boja ES; Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, MD, 20892, USA.
  • Omenn GS; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
Cell ; 182(1): 200-225.e35, 2020 07 09.
Article en En | MEDLINE | ID: mdl-32649874
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteogenómica / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteogenómica / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2020 Tipo del documento: Article