A Pilot Study for the Feasibility of Exome-Sequencing in Circulating Tumor Cells Versus Single Metastatic Biopsies in Breast Cancer.

Kaur, Pushpinder; Campo, Daniel; Porras, Tania B; Ring, Alexander; Lu, Janice; Chairez, Yvonne; Su, Yunyun; Kang, Irene; Lang, Julie E

Kaur, Pushpinder; Campo, Daniel; Porras, Tania B; Ring, Alexander; Lu, Janice; Chairez, Yvonne; Su, Yunyun; Kang, Irene; Lang, Julie E.

Afiliación

Kaur P; Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Campo D; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.
Porras TB; Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Ring A; Cancer and Blood Disease Institute, Children Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA.
Lu J; Department of Oncology and Hematology, UniversitätsSpital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland.
Chairez Y; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.
Su Y; Division of Medical Oncology, Department of Medicine and University of Southern California Norris Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
Kang I; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Lang JE; Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Int J Mol Sci ; 21(14)2020 Jul 08.

Article en En | MEDLINE | ID: mdl-32650480

Asunto(s)

Neoplasias de la Mama/genética; Neoplasias de la Mama/patología; Exoma/genética; Metástasis de la Neoplasia/genética; Células Neoplásicas Circulantes/patología; Alelos; Biopsia; Línea Celular Tumoral; Variaciones en el Número de Copia de ADN/genética; Estudios de Factibilidad; Femenino; Humanos; Mutación/genética; Proyectos Piloto; Secuenciación del Exoma/métodos

Palabras clave

breast cancer; circulating tumor cells; clinically actionable; metastasis; whole exome sequencing; whole genome amplification

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Exoma / Células Neoplásicas Circulantes / Metástasis de la Neoplasia Límite: Female / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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