Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.

Zhong, Yue; Qiu, Run-Ze; Sun, Shan-Liang; Zhao, Chao; Fan, Tian-Yuan; Chen, Min; Li, Nian-Guang; Shi, Zhi-Hao

Zhong, Yue; Qiu, Run-Ze; Sun, Shan-Liang; Zhao, Chao; Fan, Tian-Yuan; Chen, Min; Li, Nian-Guang; Shi, Zhi-Hao.

Afiliación

Zhong Y; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Qiu RZ; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Sun SL; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Zhao C; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Fan TY; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Chen M; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Li NG; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjin
Shi ZH; Department of Organic Chemistry, China Pharmaceutical University, Nanjing 211198, China.

J Med Chem ; 63(21): 12403-12428, 2020 11 12.

Article en En | MEDLINE | ID: mdl-32659083

Asunto(s)

Inhibidores de Proteínas Quinasas/química; Bibliotecas de Moléculas Pequeñas/química; Tirosina Quinasa 3 Similar a fms/antagonistas & inhibidores; Humanos; Indoles/química; Indoles/farmacología; Indoles/uso terapéutico; Leucemia Mieloide Aguda/tratamiento farmacológico; Leucemia Mieloide Aguda/patología; Inhibidores de Proteínas Quinasas/farmacología; Inhibidores de Proteínas Quinasas/uso terapéutico; Pirazoles/química; Pirazoles/farmacología; Pirazoles/uso terapéutico; Pirimidinas/química; Pirimidinas/farmacología; Pirimidinas/uso terapéutico; Transducción de Señal/efectos de los fármacos; Bibliotecas de Moléculas Pequeñas/farmacología; Bibliotecas de Moléculas Pequeñas/uso terapéutico; Urea/análogos & derivados; Urea/farmacología; Urea/uso terapéutico; Tirosina Quinasa 3 Similar a fms/metabolismo

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article

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