High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation.
Eur J Immunol
; 50(12): 2095-2098, 2020 12.
Article
en En
| MEDLINE
| ID: mdl-32697355
ABSTRACT
In CTLs High glucose-culture enhances thapsigargin-induced SOCE but decreases target recognition-induced Ca2+ influx. High glucose-culture regulates expression of ORAIs and STIMs without affecting glucose uptake. More high glucose-cultured CTLs are prone to necrosis after execution of killing.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos T Citotóxicos
/
Canales de Calcio
/
Calcio
/
Tapsigargina
/
Glucosa
Límite:
Humans
Idioma:
En
Revista:
Eur J Immunol
Año:
2020
Tipo del documento:
Article
País de afiliación:
China