A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures.

Durdevic, Dragan; Vlahovic, Tomislav; Pehar, Sanja; Miklic, Dina; Oppermann, Hermann; Bordukalo-Niksic, Tatjana; Gavrankapetanovic, Ismet; Jamakosmanovic, Mehmed; Milosevic, Milan; Martinovic, Snjezana; Sampath, T Kuber; Peric, Mihaela; Grgurevic, Lovorka; Vukicevic, Slobodan

Durdevic, Dragan; Vlahovic, Tomislav; Pehar, Sanja; Miklic, Dina; Oppermann, Hermann; Bordukalo-Niksic, Tatjana; Gavrankapetanovic, Ismet; Jamakosmanovic, Mehmed; Milosevic, Milan; Martinovic, Snjezana; Sampath, T Kuber; Peric, Mihaela; Grgurevic, Lovorka; Vukicevic, Slobodan.

Afiliación

Durdevic D; Clinical Hospital Center "Sisters of Mercy", Clinic of Traumatology, Draskoviceva 19, 10000 Zagreb, Croatia.
Vlahovic T; Clinical Hospital Center "Sisters of Mercy", Clinic of Traumatology, Draskoviceva 19, 10000 Zagreb, Croatia.
Pehar S; Laboratory for Mineralized Tissues, Centre for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 11, 10000 Zagreb, Croatia.
Miklic D; Clinical Hospital Center "Sisters of Mercy", Clinic of Traumatology, Draskoviceva 19, 10000 Zagreb, Croatia.
Oppermann H; Genera Research, Svetonedeljska 2, Kalinovica, 10436, Rakov Potok, Croatia.
Bordukalo-Niksic T; Laboratory for Mineralized Tissues, Centre for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 11, 10000 Zagreb, Croatia.
Gavrankapetanovic I; University Clinical Center Sarajevo, Clinic of Orthopedics and Traumatology, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina.
Jamakosmanovic M; University Clinical Center Sarajevo, Clinic of Orthopedics and Traumatology, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina.
Milosevic M; School of Public Health "Andrija Stampar", University of Zagreb School of Medicine, Rockefellerova 4, 10000 Zagreb, Croatia.
Martinovic S; SmartMedico, Zupanova 5, 10000 Zagreb, Croatia.
Sampath TK; perFormBiologics Inc., Holliston, MA 01746, USA.
Peric M; Department for Intracellular Communication, Centre for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 2, 10000 Zagreb, Croatia.
Grgurevic L; Laboratory for Mineralized Tissues, Centre for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 11, 10000 Zagreb, Croatia.
Vukicevic S; Laboratory for Mineralized Tissues, Centre for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 11, 10000 Zagreb, Croatia. Electronic address: slobodan.vukicevic@mef.hr.

Bone ; 140: 115551, 2020 11.

Article en En | MEDLINE | ID: mdl-32730930

Asunto(s)

Sustitutos de Huesos; Fracturas Cerradas; Proteínas Morfogenéticas Óseas; Hueso Esponjoso; Método Doble Ciego; Fijación de Fractura; Curación de Fractura; Humanos; Resultado del Tratamiento

Palabras clave

BMPs; Clinical trials; Implants; Injury/fracture healing

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sustitutos de Huesos / Fracturas Cerradas Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Bone Asunto de la revista: METABOLISMO / ORTOPEDIA Año: 2020 Tipo del documento: Article País de afiliación: Croacia

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