Applying Intravenous Immunoglobulin and Negative-Pressure Wound Therapy to Treat Refractory Pyoderma Gangrenosum: A Case Report.
Int J Low Extrem Wounds
; 20(2): 158-161, 2021 Jun.
Article
en En
| MEDLINE
| ID: mdl-32734793
ABSTRACT
Pyoderma gangrenosum (PG) is a rare chronic neutrophilic dermatosis that causes undermining ulcers. Unfortunately, standardization of PG treatment remains a challenge. In this article, we describe a case in which a 69-year-old man presented with a painful ulcer on the right lower leg. The diagnosis of PG was made after excluding other diseases. He had a history of PG on his left lower leg 2 years earlier and was cured by the treatment of systemic corticosteroids and cyclosporin A for 43 days. However, such a treatment was not effective this time. Hence, we applied intravenous immunoglobulin and negative-pressure wound therapy, and the patient was cured. Altogether, this case supports the use of intravenous immunoglobulin as an effective adjuvant for refractory PG, and indicates negative-pressure wound therapy as a treatment option to advance ulcer healing under adequate immunosuppression.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Piodermia Gangrenosa
/
Terapia de Presión Negativa para Heridas
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Int J Low Extrem Wounds
Asunto de la revista:
TRAUMATOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
China