Hepatitis D virus seroprevalence in Egyptian HBsAg-positive children: a single-center study.
Arch Virol
; 165(10): 2361-2365, 2020 Oct.
Article
en En
| MEDLINE
| ID: mdl-32743697
ABSTRACT
In this study, we investigated the seroprevalence of anti-hepatitis D virus (HDV) antibodies in hepatitis B surface antigen (HBsAg)-positive children after 25 years of obligatory vaccination of infants against hepatitis B virus. This cross-sectional study included 120 treatment-naïve HBsAg-positive children, with a male-to-female ratio of 1.81 and a mean age of 7.8 ± 3.8 years (range, 1-17 years). Mothers were positive for HBsAg in 96.6% of the cases. HBeAg-positive chronic infection was observed in 60% of the cases, HBeAg-positive chronic hepatitis in 12.5%, and HBeAg-negative chronic infection in 26.7%. Anti-HDV antibodies were not detected in any of the cases. Thus, there is a lack of anti-HDV antibodies in HBsAg-positive children, despite the current burden in adults.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Virus de la Hepatitis Delta
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Anticuerpos Antihepatitis
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Virus de la Hepatitis B
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Vacunas contra Hepatitis B
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Hepatitis D Crónica
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Hepatitis B
/
Antígenos de Superficie de la Hepatitis B
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Female
/
Humans
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Infant
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
Arch Virol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Egipto