A hairy tale: SIRT7 safeguards skin stem cells during aging.

Simon, Matthew; Emmrich, Stephan; Seluanov, Andrei; Gorbunova, Vera

Simon, Matthew; Emmrich, Stephan; Seluanov, Andrei; Gorbunova, Vera.

Afiliación

Simon M; Department of Biology, University of Rochester, Rochester, NY, USA.
Emmrich S; Department of Biology, University of Rochester, Rochester, NY, USA.
Seluanov A; Department of Biology, University of Rochester, Rochester, NY, USA.
Gorbunova V; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.

EMBO J ; 39(18): e106294, 2020 09 15.

Article en En | MEDLINE | ID: mdl-32803757

ABSTRACT

ABSTRACT

Stem cell regulation during both normal development and aging has become one of the fastest growing topics in biology. Here, new work by Li et al (2020) offers insight into the aging process within epithelial skin stem cells and highlights how SIRT7, a member of the sirtuin family of protein deacylases and mono-ADP ribosylases, protects adult hair follicle stem cells from aging by ensuring their hair cycle progression.

Asunto(s)

Folículo Piloso; Sirtuinas; Envejecimiento/genética; Animales; Ratones; Sirtuinas/genética; Fenómenos Fisiológicos de la Piel; Células Madre

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Folículo Piloso / Sirtuinas Límite: Animals Idioma: En Revista: EMBO J Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google