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Switch Control Inhibition of KIT and PDGFRA in Patients With Advanced Gastrointestinal Stromal Tumor: A Phase I Study of Ripretinib.
Janku, Filip; Abdul Razak, Albiruni R; Chi, Ping; Heinrich, Michael C; von Mehren, Margaret; Jones, Robin L; Ganjoo, Kristen; Trent, Jonathan; Gelderblom, Hans; Somaiah, Neeta; Hu, Simin; Rosen, Oliver; Su, Ying; Ruiz-Soto, Rodrigo; Gordon, Michael; George, Suzanne.
Afiliación
  • Janku F; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Abdul Razak AR; Toronto Sarcoma Program, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Chi P; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY and Department of Medicine, Weill Cornell Medicine, New York, NY.
  • Heinrich MC; Department of Medicine, Portland VA Health Care System and OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR.
  • von Mehren M; Department of Hematology and Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA.
  • Jones RL; Sarcoma Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, United Kingdom.
  • Ganjoo K; Department of Oncology, Stanford University Medical Center, Palo Alto, CA.
  • Trent J; Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL.
  • Gelderblom H; Department of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands.
  • Somaiah N; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Hu S; Deciphera Pharmaceuticals, LLC, Waltham, MA.
  • Rosen O; Deciphera Pharmaceuticals, LLC, Waltham, MA.
  • Su Y; Deciphera Pharmaceuticals, LLC, Waltham, MA.
  • Ruiz-Soto R; Deciphera Pharmaceuticals, LLC, Waltham, MA.
  • Gordon M; HonorHealth Research Institute, Scottsdale, AZ.
  • George S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
J Clin Oncol ; 38(28): 3294-3303, 2020 10 01.
Article en En | MEDLINE | ID: mdl-32804590
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Proteínas Proto-Oncogénicas c-kit / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Tumores del Estroma Gastrointestinal / Neoplasias Gastrointestinales / Naftiridinas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Oncol Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Proteínas Proto-Oncogénicas c-kit / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Tumores del Estroma Gastrointestinal / Neoplasias Gastrointestinales / Naftiridinas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Oncol Año: 2020 Tipo del documento: Article