Targeting Epigenetics in Lung Cancer.
Cold Spring Harb Perspect Med
; 11(6)2021 06 01.
Article
en En
| MEDLINE
| ID: mdl-32900703
ABSTRACT
The epigenetic landscape, which in part includes DNA methylation, chromatin organization, histone modifications, and noncoding RNA regulation, greatly contributes to the heterogeneity that makes developing effective therapies for lung cancer challenging. This review will provide an overview of the epigenetic alterations that have been implicated in all aspects of cancer pathogenesis and progression as well as summarize clinical applications for targeting epigenetics in the treatment of lung cancer.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Epigenómica
/
Neoplasias Pulmonares
Límite:
Humans
Idioma:
En
Revista:
Cold Spring Harb Perspect Med
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos