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Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder.
Egervari, Gabor; Akpoyibo, Diana; Rahman, Tanni; Fullard, John F; Callens, James E; Landry, Joseph A; Ly, Annie; Zhou, Xianxiao; Warren, Noël; Hauberg, Mads E; Hoffman, Gabriel; Ellis, Randy; Ferland, Jacqueline-Marie N; Miller, Michael L; Keller, Eva; Zhang, Bin; Roussos, Panos; Hurd, Yasmin L.
Afiliación
  • Egervari G; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Akpoyibo D; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Rahman T; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Fullard JF; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Callens JE; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Landry JA; Addiction Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ly A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhou X; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Warren N; Addiction Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Hauberg ME; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Hoffman G; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ellis R; Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ferland JN; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Miller ML; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Keller E; Addiction Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhang B; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Roussos P; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Hurd YL; Addiction Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nat Commun ; 11(1): 4634, 2020 09 14.
Article en En | MEDLINE | ID: mdl-32929078
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatina / Cuerpo Estriado / Proteínas Proto-Oncogénicas c-fyn / Terapia Molecular Dirigida / Dependencia de Heroína Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatina / Cuerpo Estriado / Proteínas Proto-Oncogénicas c-fyn / Terapia Molecular Dirigida / Dependencia de Heroína Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos