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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models.
Lee-Law, Pui Y; Olaizola, Paula; Caballero-Camino, Francisco J; Izquierdo-Sanchez, Laura; Rodrigues, Pedro M; Santos-Laso, Alvaro; Azkargorta, Mikel; Elortza, Felix; Martinez-Chantar, Maria L; Perugorria, Maria J; Aspichueta, Patricia; Marzioni, Marco; LaRusso, Nicholas F; Bujanda, Luis; Drenth, Joost P H; Banales, Jesus M.
Afiliación
  • Lee-Law PY; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain; Department of Gastroenterology & Hepatology, Radboud University Nijmegen Medical Center, The Netherlands.
  • Olaizola P; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Caballero-Camino FJ; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Izquierdo-Sanchez L; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos I
  • Rodrigues PM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Santos-Laso A; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain.
  • Azkargorta M; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), Spain; Proteomics Platform, Center for Cooperative Research in Biosciences (CIC bioGUNE), ProteoRed-ISCIII, Bizkaia Science and Technology Park, Derio, Spain.
  • Elortza F; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), Spain; Proteomics Platform, Center for Cooperative Research in Biosciences (CIC bioGUNE), ProteoRed-ISCIII, Bizkaia Science and Technology Park, Derio, Spain.
  • Martinez-Chantar ML; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos III"), Spain; Liver Disease Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Spain.
  • Perugorria MJ; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos I
  • Aspichueta P; Department of Physiology, Faculty of Medicine and Nursing, University of Basque Country UPV/EHU, Leioa, Spain; Biocruces Bizkaia Health Research Institute, Cruces University Hospital, Barakaldo, Spain.
  • Marzioni M; "Università Politecnica delle Marche", Department of Gastroenterology, Ancona, Italy.
  • LaRusso NF; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Bujanda L; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos I
  • Drenth JPH; Department of Gastroenterology & Hepatology, Radboud University Nijmegen Medical Center, The Netherlands.
  • Banales JM; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute - Donostia University Hospital -, University of the Basque Country (UPV/EHU), San Sebastian, Spain; National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd, "Instituto de Salud Carlos I
J Hepatol ; 74(2): 394-406, 2021 02.
Article en En | MEDLINE | ID: mdl-32950589
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: S-Adenosilmetionina / Quistes / ARN Interferente Pequeño / Enzimas Ubiquitina-Conjugadoras / Sumoilación / Hepatopatías Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: S-Adenosilmetionina / Quistes / ARN Interferente Pequeño / Enzimas Ubiquitina-Conjugadoras / Sumoilación / Hepatopatías Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos