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Neuron-specific deletion of presenilin enhancer2 causes progressive astrogliosis and age-related neurodegeneration in the cortex independent of the Notch signaling.
Bi, Hui-Ru; Zhou, Cui-Hua; Zhang, Yi-Zhi; Cai, Xu-Dong; Ji, Mu-Huo; Yang, Jian-Jun; Chen, Gui-Quan; Hu, Yi-Min.
Afiliación
  • Bi HR; Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Study, Medical School, Nanjing University, Nanjing, China.
  • Zhou CH; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou, China.
  • Zhang YZ; Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Study, Medical School, Nanjing University, Nanjing, China.
  • Cai XD; Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Study, Medical School, Nanjing University, Nanjing, China.
  • Ji MH; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  • Yang JJ; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  • Chen GQ; Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Study, Medical School, Nanjing University, Nanjing, China.
  • Hu YM; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou, China.
CNS Neurosci Ther ; 27(2): 174-185, 2021 02.
Article en En | MEDLINE | ID: mdl-32961023
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Corteza Cerebral / Receptores Notch / Secretasas de la Proteína Precursora del Amiloide / Gliosis / Neuronas Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: CNS Neurosci Ther Asunto de la revista: NEUROLOGIA / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Envejecimiento / Corteza Cerebral / Receptores Notch / Secretasas de la Proteína Precursora del Amiloide / Gliosis / Neuronas Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: CNS Neurosci Ther Asunto de la revista: NEUROLOGIA / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: China