Synthesis and Biological Evaluation of Novel Benodanil-Heterocyclic Carboxamide Hybrids as a Potential Succinate Dehydrogenase Inhibitors.

Yang, Jian; Zhao, Yongtian; Wan, Jun; Jiang, Mingfang; Jin, Hong; Tao, Ke; Hou, Taiping

Yang, Jian; Zhao, Yongtian; Wan, Jun; Jiang, Mingfang; Jin, Hong; Tao, Ke; Hou, Taiping.

Afiliación

Yang J; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Zhao Y; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Wan J; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Jiang M; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Jin H; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Tao K; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.
Hou T; Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China.

Molecules ; 25(18)2020 Sep 18.

Article en En | MEDLINE | ID: mdl-32962104

Asunto(s)

Antifúngicos/síntesis química; Benzamidas/química; Inhibidores Enzimáticos/química; Compuestos Heterocíclicos/química; Succinato Deshidrogenasa/antagonistas & inhibidores; Amidas/química; Antifúngicos/metabolismo; Antifúngicos/farmacología; Benzamidas/farmacología; Sitios de Unión; Diseño de Fármacos; Inhibidores Enzimáticos/metabolismo; Inhibidores Enzimáticos/farmacología; Pruebas de Sensibilidad Microbiana; Simulación del Acoplamiento Molecular; Rhizoctonia/efectos de los fármacos; Rhizoctonia/aislamiento & purificación; Relación Estructura-Actividad; Succinato Deshidrogenasa/metabolismo

Palabras clave

antifungal activity; benodanil-heterocyclic carboxamide hybrids; molecular docking; succinate dehydrogenase inhibitor

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Succinato Deshidrogenasa / Benzamidas / Inhibidores Enzimáticos / Compuestos Heterocíclicos / Antifúngicos Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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