Heterogeneity of telomerase reverse transcriptase mutation and expression, telomerase activity and telomere length across human cancer cell lines cultured in vitro.

Dratwa, Marta; Wysoczanska, Barbara; Turlej, Eliza; Anisiewicz, Artur; Maciejewska, Magdalena; Wietrzyk, Joanna; Bogunia-Kubik, Katarzyna

Dratwa, Marta; Wysoczanska, Barbara; Turlej, Eliza; Anisiewicz, Artur; Maciejewska, Magdalena; Wietrzyk, Joanna; Bogunia-Kubik, Katarzyna.

Afiliación

Dratwa M; Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Wysoczanska B; Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Turlej E; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Anisiewicz A; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Maciejewska M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Wietrzyk J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Bogunia-Kubik K; Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland. Electronic address: katarzyna.bogunia-kubik@hirszfeld.pl.

Exp Cell Res ; 396(1): 112298, 2020 11 01.

Article en En | MEDLINE | ID: mdl-32971118

Asunto(s)

Mutación; Telomerasa/genética; Homeostasis del Telómero; Telómero/química; Células A549; Línea Celular; Línea Celular Tumoral; Expresión Génica; Células HL-60; Células HT29; Humanos; Células K562; Células MCF-7; Especificidad de Órganos; Regiones Promotoras Genéticas; Células THP-1; Telomerasa/metabolismo; Telómero/metabolismo

Palabras clave

Neoplastic haematological and solid tumour human cell lines; TERT expression; TERTp mutations; Telomerase activity; Telomerase reverse transcriptase; Telomere length

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Telómero / Telomerasa / Homeostasis del Telómero / Mutación Límite: Humans Idioma: En Revista: Exp Cell Res Año: 2020 Tipo del documento: Article País de afiliación: Polonia

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