YB-1 Interferes with TNF&#945;-TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNF&#945; Signaling.

Hessman, Christopher L; Hildebrandt, Josephine; Shah, Aneri; Brandt, Sabine; Bock, Antonia; Frye, Björn C; Raffetseder, Ute; Geffers, Robert; Brunner-Weinzierl, Monika C; Isermann, Berend; Mertens, Peter R; Lindquist, Jonathan A

YB-1 Interferes with TNFα-TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFα Signaling.

Hessman, Christopher L; Hildebrandt, Josephine; Shah, Aneri; Brandt, Sabine; Bock, Antonia; Frye, Björn C; Raffetseder, Ute; Geffers, Robert; Brunner-Weinzierl, Monika C; Isermann, Berend; Mertens, Peter R; Lindquist, Jonathan A.

Afiliación

Hessman CL; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Hildebrandt J; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Shah A; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Brandt S; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Bock A; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Frye BC; Department of Nephrology and Clinical Immunology, RWTH Aachen University, 52074 Aachen, Germany.
Raffetseder U; Department of Nephrology and Clinical Immunology, RWTH Aachen University, 52074 Aachen, Germany.
Geffers R; Genome Analytics Research Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Brunner-Weinzierl MC; Department of Experimental Pediatrics, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Isermann B; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany.
Mertens PR; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Lindquist JA; Clinic of Nephrology and Hypertension, Diabetes and Endocrinology, Otto-von-Guericke University, 39120 Magdeburg, Germany.

Int J Mol Sci ; 21(19)2020 Sep 25.

Article en En | MEDLINE | ID: mdl-32992926

Asunto(s)

Macrófagos/inmunología; Progranulinas/inmunología; Receptores del Factor de Necrosis Tumoral/inmunología; Transducción de Señal/inmunología; Factores de Transcripción/inmunología; Factor de Necrosis Tumoral alfa/inmunología; Animales; Macrófagos/patología; Ratones; Progranulinas/genética; Células RAW 264.7; Receptores del Factor de Necrosis Tumoral/genética; Transducción de Señal/genética; Factores de Transcripción/genética; Factor de Necrosis Tumoral alfa/genética

Palabras clave

DNA binding protein-B (DbpB); Y-box binding protein-1 (YB-1); immune modulation; inflammation; macrophage; progranulin; signaling; tumor necrosis factor alpha (TNFα)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Transducción de Señal / Factor de Necrosis Tumoral alfa / Receptores del Factor de Necrosis Tumoral / Progranulinas / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Alemania

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