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Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Darby, John F; Vidler, Lewis R; Simpson, Peter J; Al-Lazikani, Bissan; Matthews, Stephen J; Sharp, Swee Y; Pearl, Laurence H; Hoelder, Swen; Workman, Paul.
Afiliación
  • Darby JF; Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK.
  • Vidler LR; Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK.
  • Simpson PJ; Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK.
  • Al-Lazikani B; Bruker UK Ltd, Banner Lane, Coventry, CV4 9GH, UK.
  • Matthews SJ; Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK.
  • Sharp SY; Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK.
  • Pearl LH; Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SM2 5NG, UK.
  • Hoelder S; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, UK.
  • Workman P; Division of Structural Biology, The Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
Sci Rep ; 10(1): 16000, 2020 09 29.
Article en En | MEDLINE | ID: mdl-32994435
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bibliotecas de Moléculas Pequeñas / Proteínas de Choque Térmico Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
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Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bibliotecas de Moléculas Pequeñas / Proteínas de Choque Térmico Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido