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Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial).
Duvignaud, Alexandre; Lhomme, Edouard; Pistone, Thierry; Onaisi, Racha; Sitta, Rémi; Journot, Valérie; Nguyen, Duc; Peiffer-Smadja, Nathan; Crémer, Antoine; Bouchet, Stéphane; Darnaud, Thomas; Poitrenaud, Delphine; Piroth, Lionel; Binquet, Christine; Michel, Jean-François; Lefèvre, Benjamin; Lebeaux, David; Lebel, Josselin; Dupouy, Julie; Roussillon, Caroline; Gimbert, Anne; Wittkop, Linda; Thiébaut, Rodolphe; Orne-Gliemann, Joanna; Joseph, Jean-Philippe; Richert, Laura; Anglaret, Xavier; Malvy, Denis.
Afiliación
  • Duvignaud A; CHU Bordeaux, Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, F-33000, Bordeaux, France. alexandre.duvignaud@chu-bordeaux.fr.
  • Lhomme E; Inserm U1219, Univ. Bordeaux, IRD, F-33000, Bordeaux, France. alexandre.duvignaud@chu-bordeaux.fr.
  • Pistone T; Univ. Bordeaux, Inserm, CHU Bordeaux, CIC 1401, EUCLID/F-CRIN Clinical Trials Platform, F-33000, Bordeaux, France.
  • Onaisi R; Univ. Bordeaux, Department of Public Health, Inserm Bordeaux Population Health Research Centre, Inria SISTM, F-33000, Bordeaux, France.
  • Sitta R; CHU Bordeaux, Pôle de Santé Publique, F-33000, Bordeaux, France.
  • Journot V; CHU Bordeaux, Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, F-33000, Bordeaux, France.
  • Nguyen D; Inserm U1219, Univ. Bordeaux, IRD, F-33000, Bordeaux, France.
  • Peiffer-Smadja N; Department of General Practice, Univ. Bordeaux, F-33000, Bordeaux, France.
  • Crémer A; Univ. Bordeaux, Inserm, CHU Bordeaux, CIC 1401, EUCLID/F-CRIN Clinical Trials Platform, F-33000, Bordeaux, France.
  • Bouchet S; CHU Bordeaux, Pôle de Santé Publique, F-33000, Bordeaux, France.
  • Darnaud T; Inserm U1219, Univ. Bordeaux, IRD, F-33000, Bordeaux, France.
  • Poitrenaud D; CHU Bordeaux, Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, F-33000, Bordeaux, France.
  • Piroth L; Inserm U1219, Univ. Bordeaux, IRD, F-33000, Bordeaux, France.
  • Binquet C; CHU Bichat Claude Bernard, Department of Infectious Diseases and Tropical Medicine, APHP, F-75000, Paris, France.
  • Michel JF; Université de Paris, IAME, INSERM, F-75018, Paris, France.
  • Lefèvre B; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, UK.
  • Lebeaux D; Department of Cardiology - Hypertension, CHU Bordeaux, F-33000, Bordeaux, France.
  • Lebel J; Inserm U1219, Univ. Bordeaux, F-33000, Bordeaux, France.
  • Dupouy J; Inserm U1219, Univ. Bordeaux, F-33000, Bordeaux, France.
  • Roussillon C; Department of Pharmacology and Toxicology, CHU Bordeaux, F-33000, Bordeaux, France.
  • Gimbert A; Centre Hospitalier de Bastia, Service de Chirurgie Spécialisée & Unité de Recherche Clinique, F-20200, Bastia, France.
  • Wittkop L; Department of Infectious Diseases and Tropical Medicine, Centre Hospitalier d'Ajaccio, F-20090, Ajaccio, France.
  • Thiébaut R; Department of Infectious Diseases and Tropical Medicine, CHU Dijon, F-21079, Dijon, France.
  • Orne-Gliemann J; Inserm U1432, Univ. Bourgogne, F-21000, Dijon, France.
  • Joseph JP; Inserm, CHU Dijon, CIC-EC 1432, F-21000, Dijon, France.
  • Richert L; Centre Medical de Steinsel, Steinsel, Luxembourg.
  • Anglaret X; Formation Spécialisée en Medecine Generale (FSMG), Université de Luxembourg, Luxembourg City, Luxembourg.
  • Malvy D; Department of Infectious Diseases and Tropical Medicine, CHU Nancy, F-54000, Nancy, France.
Trials ; 21(1): 846, 2020 Oct 13.
Article en En | MEDLINE | ID: mdl-33050924
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pacientes Ambulatorios / Neumonía Viral / Infecciones por Coronavirus / Terapias en Investigación / Betacoronavirus Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Francia
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pacientes Ambulatorios / Neumonía Viral / Infecciones por Coronavirus / Terapias en Investigación / Betacoronavirus Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans País/Región como asunto: Europa Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Francia