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Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Bao, Erik L; Nandakumar, Satish K; Liao, Xiaotian; Bick, Alexander G; Karjalainen, Juha; Tabaka, Marcin; Gan, Olga I; Havulinna, Aki S; Kiiskinen, Tuomo T J; Lareau, Caleb A; de Lapuente Portilla, Aitzkoa L; Li, Bo; Emdin, Connor; Codd, Veryan; Nelson, Christopher P; Walker, Christopher J; Churchhouse, Claire; de la Chapelle, Albert; Klein, Daryl E; Nilsson, Björn; Wilson, Peter W F; Cho, Kelly; Pyarajan, Saiju; Gaziano, J Michael; Samani, Nilesh J; Regev, Aviv; Palotie, Aarno; Neale, Benjamin M; Dick, John E; Natarajan, Pradeep; O'Donnell, Christopher J; Daly, Mark J; Milyavsky, Michael; Kathiresan, Sekar; Sankaran, Vijay G.
Afiliación
  • Bao EL; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Nandakumar SK; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Liao X; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bick AG; Harvard-MIT Health Sciences and Technology, Harvard Medical School, Boston, MA, USA.
  • Karjalainen J; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Tabaka M; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Gan OI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Havulinna AS; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Kiiskinen TTJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Lareau CA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • de Lapuente Portilla AL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Li B; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Emdin C; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Codd V; VA Boston Healthcare, Section of Cardiology, Boston, MA, USA.
  • Nelson CP; Harvard Medical School, Boston, MA, USA.
  • Walker CJ; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
  • Churchhouse C; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • de la Chapelle A; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Klein DE; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Nilsson B; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
  • Wilson PWF; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
  • Cho K; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Pyarajan S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Gaziano JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Samani NJ; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, USA.
  • Regev A; Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
  • Palotie A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Neale BM; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Dick JE; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • Natarajan P; National Institute for Health Research (NIHR) Leicester Biomedical Centre, Glenfield Hospital, Leicester, UK.
  • O'Donnell CJ; Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK.
  • Daly MJ; National Institute for Health Research (NIHR) Leicester Biomedical Centre, Glenfield Hospital, Leicester, UK.
  • Milyavsky M; Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
  • Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sankaran VG; Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Nature ; 586(7831): 769-775, 2020 10.
Article en En | MEDLINE | ID: mdl-33057200

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Predisposición Genética a la Enfermedad / Trastornos Mieloproliferativos / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Predisposición Genética a la Enfermedad / Trastornos Mieloproliferativos / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos