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Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Tree, Julia A; Turnbull, Jeremy E; Buttigieg, Karen R; Elmore, Michael J; Coombes, Naomi; Hogwood, John; Mycroft-West, Courtney J; Lima, Marcelo A; Skidmore, Mark A; Karlsson, Richard; Chen, Yen-Hsi; Yang, Zhang; Spalluto, Cosma Mirella; Staples, Karl J; Yates, Edwin A; Gray, Elaine; Singh, Dave; Wilkinson, Tom; Page, Clive P; Carroll, Miles W.
Afiliación
  • Tree JA; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
  • Turnbull JE; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK.
  • Buttigieg KR; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Elmore MJ; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
  • Coombes N; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
  • Hogwood J; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
  • Mycroft-West CJ; Haemostasis Section, Biotherapeutics, National Institute for Biological Standards and Control (NIBSC), Potters Bar, UK.
  • Lima MA; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
  • Skidmore MA; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
  • Karlsson R; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
  • Chen YH; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Yang Z; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Spalluto CM; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Staples KJ; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
  • Yates EA; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
  • Gray E; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK.
  • Singh D; Haemostasis Section, Biotherapeutics, National Institute for Biological Standards and Control (NIBSC), Potters Bar, UK.
  • Wilkinson T; Sackler Institute of Pulmonary Pharmacology, King's College London, London, UK.
  • Page CP; Medicines Evaluation Unit, University of Manchester, Manchester University Hospital NHS Foundation Trust, Manchester, UK.
  • Carroll MW; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
Br J Pharmacol ; 178(3): 626-635, 2021 02.
Article en En | MEDLINE | ID: mdl-33125711
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Heparina / SARS-CoV-2 Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Heparina / SARS-CoV-2 Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido