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Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure.
Ko, Kenta; Suzuki, Takehiro; Ishikawa, Ryota; Hattori, Natsuko; Ito, Risako; Umehara, Kenta; Furihata, Tomomi; Dohmae, Naoshi; Linhardt, Robert J; Igarashi, Kazuei; Toida, Toshihiko; Higashi, Kyohei.
Afiliación
  • Ko K; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Suzuki T; RIKEN Center for Sustainable Resource Science, Wako, Japan.
  • Ishikawa R; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Hattori N; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Ito R; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
  • Umehara K; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Furihata T; School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Dohmae N; RIKEN Center for Sustainable Resource Science, Wako, Japan.
  • Linhardt RJ; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
  • Igarashi K; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan; Amine Pharma Research Institute, Innovation Plaza at Chiba University, Chiba, Japan.
  • Toida T; Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
  • Higashi K; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan. Electronic address: higase@rs.tus.ac.jp.
J Biol Chem ; 295(52): 18614-18624, 2020 12 25.
Article en En | MEDLINE | ID: mdl-33127645
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acroleína / Endotelio Vascular / Isquemia Encefálica / Glicocálix / Accidente Cerebrovascular Isquémico / Glucuronidasa Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acroleína / Endotelio Vascular / Isquemia Encefálica / Glicocálix / Accidente Cerebrovascular Isquémico / Glucuronidasa Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article País de afiliación: Japón