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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling.
Gally, Fabienne; Sasse, Sarah K; Kurche, Jonathan S; Gruca, Margaret A; Cardwell, Jonathan H; Okamoto, Tsukasa; Chu, Hong W; Hou, Xiaomeng; Poirion, Olivier B; Buchanan, Justin; Preissl, Sebastian; Ren, Bing; Colgan, Sean P; Dowell, Robin D; Yang, Ivana V; Schwartz, David A; Gerber, Anthony N.
Afiliación
  • Gally F; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado, USA.
  • Sasse SK; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Kurche JS; Department of Medicine, National Jewish Health, Denver, Colorado, USA.
  • Gruca MA; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Cardwell JH; BioFrontiers Institute, University of Colorado-Boulder (CU Boulder), Boulder, Colorado, USA.
  • Okamoto T; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Chu HW; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Hou X; Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
  • Poirion OB; Department of Medicine, National Jewish Health, Denver, Colorado, USA.
  • Buchanan J; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA.
  • Preissl S; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA.
  • Ren B; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA.
  • Colgan SP; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA.
  • Dowell RD; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, California, USA.
  • Yang IV; Ludwig Institute for Cancer Research, La Jolla, California, USA.
  • Schwartz DA; Department of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Gerber AN; BioFrontiers Institute, University of Colorado-Boulder (CU Boulder), Boulder, Colorado, USA.
JCI Insight ; 6(2)2021 01 25.
Article en En | MEDLINE | ID: mdl-33320836

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis Pulmonar Idiopática / Mucina 5B Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: JCI Insight Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis Pulmonar Idiopática / Mucina 5B Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: JCI Insight Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos