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Optogenetics: The Art of Illuminating Complex Signaling Pathways.
Shaaya, Mark; Fauser, Jordan; Karginov, Andrei V.
Afiliación
  • Shaaya M; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.
  • Fauser J; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.
  • Karginov AV; Department of Pharmacology and Regenerative Medicine, The University of Illinois at Chicago, College of Medicine, Chicago, Illinois.
Physiology (Bethesda) ; 36(1): 52-60, 2021 01 01.
Article en En | MEDLINE | ID: mdl-33325819
Dissection of cell signaling requires tools that can mimic spatiotemporal dynamics of individual pathways in living cells. Optogenetic methods enable manipulation of signaling processes with precise timing and local control. In this review, we describe recent optogenetic approaches for regulation of cell signaling, highlight their advantages and limitations, and discuss examples of their application.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Optogenética Idioma: En Revista: Physiology (Bethesda) Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Optogenética Idioma: En Revista: Physiology (Bethesda) Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article