Rehabilitation Interventions in the Multidisciplinary Management of Patients With Sclerotic Graft-Versus-Host Disease of the Skin and Fascia.
Arch Phys Med Rehabil
; 102(4): 776-788, 2021 04.
Article
en En
| MEDLINE
| ID: mdl-33347890
ABSTRACT
Graft-versus-host disease (GVHD) is a multisystemic disorder that affects 30%-80% of patients who undergo allogeneic hematopoietic stem cell transplantation 10%-15% of GVHD patients develop sclerotic features affecting the skin or deeper tissues, leading to functional limitations and poor quality of life. There is limited literature regarding the indications and efficacy of specific rehabilitative interventions in sclerotic GVHD (sclGVHD). In this article, we summarize the current evidence supporting rehabilitation intervention in sclGVHD and offer our approach to the multidisciplinary management of this disease. In addition, we review techniques that have been employed in other sclerotic skin diseases (eg, iontophoresis, extracorporeal shock waves, botulinum toxin A, adipose derived stromal vascular fraction), but that require further validation in the sclGVHD setting. Ultimately, optimal care for this complex disease requires a multidisciplinary approach that includes a rehabilitation and adaptive program tailored to each patient's needs.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Grupo de Atención al Paciente
/
Enfermedades de la Piel
/
Terapia Ocupacional
/
Modalidades de Fisioterapia
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Trasplante de Células Madre Hematopoyéticas
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Enfermedad Injerto contra Huésped
Límite:
Humans
Idioma:
En
Revista:
Arch Phys Med Rehabil
Año:
2021
Tipo del documento:
Article