Synthesis of Sulfonamide-Based Ynamides and Ynamines in Water.
J Org Chem
; 86(2): 1938-1947, 2021 01 15.
Article
en En
| MEDLINE
| ID: mdl-33356269
ABSTRACT
Ynamides, though relatively more stable than ynamines, are still moisture-sensitive and prone to hydration especially under acidic and heating conditions. Here we report an environmentally benign, robust protocol to synthesize sulfonamide-based ynamides and arylynamines via Sonogashira coupling reactions in water, using a readily available quaternary ammonium salt as the surfactant.
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Banco de datos:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Año:
2021
Tipo del documento:
Article
País de afiliación:
China