Efficacy of treatment for acneiform eruptions related to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for non-small cell lung cancer (NSCLC): A protocol of systematic review and network meta-analysis.
Medicine (Baltimore)
; 100(1): e23875, 2021 Jan 08.
Article
en En
| MEDLINE
| ID: mdl-33429746
ABSTRACT
BACKGROUND:
Acneiform eruptions from epidermal growth factor receptor tyrosine kinase inhibitors is a frequent adverse event in non-small cell lung cancer patients but the efficacy of its treatment including antibiotics, corticosteroid, sunscreen is still poorly understood.METHODS:
Eight electronic databases (PubMed, EMBASE, ClinicalTrials.gov, etc) will be searched from inception to April 2020. Risk of bias of randomized controlled trials will be assessed in terms of the Risk of Bias 2 (RoB 2) tool. Eligible randomized controlled trials will be enrolled for a Bayesian network meta-analysis using R software.RESULTS:
This study is still ongoing and the results will be submitted and published in a peer-reviewed scientific journal.CONCLUSION:
We hope the results of this study will provide reliable evidence for the management of acneiform due to epidermal growth factor receptor tyrosine kinase inhibitors for non-small cell lung cancer. ETHICS AND DISSEMINATION Ethical approval is not applicable for this study is based on published trials. PROTOCOL REGISTRATION NUMBER CRD42020206724.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Protocolos Clínicos
/
Erupciones Acneiformes
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Carcinoma de Pulmón de Células no Pequeñas
Tipo de estudio:
Clinical_trials
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Guideline
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2021
Tipo del documento:
Article