The effect of atorvastatin on the common carotid artery intima-media thickness in patients with ischemic stroke.
Acta Clin Croat
; 59(2): 223-226, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-33456108
ABSTRACT
Occlusion of the initial segment of internal carotid artery is the most common reason for vascular events in the brain. The purpose of this study was to investigate the effect of one-year treatment with atorvastatin on intima-media thickness (IMT) of carotid arteries as a measure of atherosclerosis in stroke patients. In this prospective interventional study, 44 patients with ischemic stroke were investigated. Patients were treated with atorvastatin 40 mg once a day for one year. IMT of carotid arteries was measured by extracranial Doppler ultrasonography in the distal part of the common carotid artery at the beginning of the study, at 6 months and one year of treatment with atorvastatin. The IMT of both right and left carotid arteries decreased after 6- and 12-month atorvastatin treatment. Based on the results of this study, long-term administration of atorvastatin was associated with reduction in carotid artery IMT in patients with ischemic stroke. Such a decrease in IMT may prevent subsequent stroke or cardiovascular events in these patients.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Isquemia Encefálica
/
Inhibidores de Hidroximetilglutaril-CoA Reductasas
/
Accidente Cerebrovascular
/
Grosor Intima-Media Carotídeo
/
Atorvastatina
/
Accidente Cerebrovascular Isquémico
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Acta Clin Croat
Asunto de la revista:
MEDICINA
Año:
2020
Tipo del documento:
Article