Your browser doesn't support javascript.
loading
Nebulosa recovers single-cell gene expression signals by kernel density estimation.
Alquicira-Hernandez, Jose; Powell, Joseph E.
Afiliación
  • Alquicira-Hernandez J; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.
  • Powell JE; Computational Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia.
Bioinformatics ; 37(16): 2485-2487, 2021 Aug 25.
Article en En | MEDLINE | ID: mdl-33459785
ABSTRACT

SUMMARY:

Data sparsity in single-cell experiments prevents an accurate assessment of gene expression when visualized in a low-dimensional space. Here, we introduce Nebulosa, an R package that uses weighted kernel density estimation to recover signals lost through drop-out or low expression. AVAILABILITY AND IMPLEMENTATION Nebulosa can be easily installed from www.github.com/powellgenomicslab/Nebulosa. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Australia