Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer.

Young, Graeme P; Symonds, Erin L; Nielsen, Hans Jørgen; Ferm, Linnea; Christensen, Ib J; Dekker, Evelien; van der Vlugt, Manon; Mallant-Hent, Rosalie C; Boulter, Nicky; Yu, Betty; Chan, Michelle; Tevz, Gregor; LaPointe, Lawrence C; Pedersen, Susanne K

Young, Graeme P; Symonds, Erin L; Nielsen, Hans Jørgen; Ferm, Linnea; Christensen, Ib J; Dekker, Evelien; van der Vlugt, Manon; Mallant-Hent, Rosalie C; Boulter, Nicky; Yu, Betty; Chan, Michelle; Tevz, Gregor; LaPointe, Lawrence C; Pedersen, Susanne K.

Afiliación

Young GP; Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia.
Symonds EL; Flinders Health and Medical Research Institute, Flinders University, Adelaide, Australia.
Nielsen HJ; Bowel Health Service, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Ferm L; Department of Surgical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
Christensen IJ; Department of Surgical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
Dekker E; Department of Surgical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
van der Vlugt M; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Mallant-Hent RC; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Boulter N; Department of Gastroenterology, Flevo Hospital, Almere, The Netherlands.
Yu B; Clinical Genomics Pty Ltd, North Ryde, NSW, Australia.
Chan M; Clinical Genomics Pty Ltd, North Ryde, NSW, Australia.
Tevz G; Clinical Genomics Pty Ltd, North Ryde, NSW, Australia.
LaPointe LC; Clinical Genomics Pty Ltd, North Ryde, NSW, Australia.
Pedersen SK; Clinical Genomics Technologies Ltd, Edison, USA.

Clin Epigenetics ; 13(1): 14, 2021 01 21.

Article en En | MEDLINE | ID: mdl-33478584

Asunto(s)

Biomarcadores de Tumor/sangre; Biomarcadores de Tumor/genética; Neoplasias Colorrectales/diagnóstico; Neoplasias Colorrectales/genética; Metilación de ADN; ADN de Neoplasias/sangre; ADN de Neoplasias/genética; Tamizaje Masivo/métodos; Adulto; Anciano; Anciano de 80 o más Años; Estudios Transversales; Femenino; Humanos; Masculino; Persona de Mediana Edad; Estudios Retrospectivos; Sensibilidad y Especificidad

Palabras clave

BCAT1; Colorectal cancer screening; IKZF1; IRF4; Methylated circulating tumor DNA

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN de Neoplasias / Neoplasias Colorrectales / Biomarcadores de Tumor / Tamizaje Masivo / Metilación de ADN Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Epigenetics Año: 2021 Tipo del documento: Article País de afiliación: Australia

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