Functional phenotyping of the CYP2D6 probe drug codeine in the horse.

Gretler, S R; Finno, C J; Kass, P H; Knych, H K

Gretler, S R; Finno, C J; Kass, P H; Knych, H K.

Afiliación

Gretler SR; K.L. Maddy Equine Analytical Pharmacology Laboratory, University of California-Davis, School of Veterinary Medicine, 620 West Health Science Drive, Davis, CA, 95616, USA.
Finno CJ; Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, USA.
Kass PH; Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, USA.
Knych HK; K.L. Maddy Equine Analytical Pharmacology Laboratory, University of California-Davis, School of Veterinary Medicine, 620 West Health Science Drive, Davis, CA, 95616, USA. hkknych@ucdavis.edu.

BMC Vet Res ; 17(1): 77, 2021 Feb 13.

Article en En | MEDLINE | ID: mdl-33581736

Asunto(s)

Codeína/metabolismo; Codeína/farmacocinética; Citocromo P-450 CYP2D6/metabolismo; Animales; Codeína/análogos & derivados; Codeína/sangre; Citocromo P-450 CYP2D6/genética; Femenino; Caballos; Masculino; Derivados de la Morfina/metabolismo; Fenotipo; Polimorfismo Genético

Palabras clave

CYP450; Codeine; Horse; Metabolic ratio; Phenotyping

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Codeína / Citocromo P-450 CYP2D6 Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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