Venous drainage of the femur permits passage of 100-micron particles.
J Orthop Res
; 6(5): 671-5, 1988.
Article
en En
| MEDLINE
| ID: mdl-3404324
ABSTRACT
Iatrogenic metastasis of bone tumor is reportedly increased if aggregates of tumor cells enter the circulation. The current study used a previously developed animal model to explore the movement of 25-, 50-, and 100-micron-diameter particles from an experimental femur biopsy site into the circulation. The results indicate that cell aggregate-sized particles can enter the circulation from the femur at a rate similar to that of the 15-micron particles used in previous studies. Arterial blood samples collected during and after the injection of particles contained no 50- or 100-micron particles, suggesting that the lung is an effective filter for these larger particles.
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Banco de datos:
MEDLINE
Asunto principal:
Fémur
/
Células Neoplásicas Circulantes
Límite:
Animals
Idioma:
En
Revista:
J Orthop Res
Año:
1988
Tipo del documento:
Article