Miliaria crystallina induced by idarubicin and all-trans-retinoic acid: Two case reports.
Australas J Dermatol
; 62(3): e408-e410, 2021 Aug.
Article
en En
| MEDLINE
| ID: mdl-34106466
ABSTRACT
Miliaria crystallina is a benign, self-limiting disorder of the eccrine sweat glands characterized by the obstruction of the sweat ducts, which leads to secondary sweat retention into stratum corneum. We present two patients with MC during treatment with idarubicin and all-trans-retinoic acid (ATRA) for acute promyelocytic leukaemia (APL). Anthracyclines can be excreted through sweat and induce MC through exfoliation. The use of idarubicin in combination with ATRA would favour the process of producing a peeling effect. Reports of MC associated with idarubicin and ATRA are scarce. Recognizing this benign entity and its triggers will help to differentiate it from other skin reactions, improving the management of patients by avoiding unnecessary studies and treatments.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Tretinoina
/
Idarrubicina
/
Protocolos de Quimioterapia Combinada Antineoplásica
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Miliaria
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Antibióticos Antineoplásicos
Límite:
Humans
Idioma:
En
Revista:
Australas J Dermatol
Año:
2021
Tipo del documento:
Article
País de afiliación:
España