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Effect of Glycero-(9,10-trioxolane)-trialeate on the Physicochemical Properties of Non-Woven Polylactic Acid Fiber Materials.
Olkhov, Anatoliy; Alexeeva, Olga; Konstantinova, Marina; Podmasterev, Vyacheslav; Tyubaeva, Polina; Borunova, Anna; Siracusa, Valentina; Iordanskii, Alex L.
Afiliación
  • Olkhov A; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119991 Moscow, Russia.
  • Alexeeva O; Department of Chemistry and Physics, Plekhanov Russian University of Economics, Stremyanny Ln 36, 117997 Moscow, Russia.
  • Konstantinova M; N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119334 Moscow, Russia.
  • Podmasterev V; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119991 Moscow, Russia.
  • Tyubaeva P; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119991 Moscow, Russia.
  • Borunova A; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119991 Moscow, Russia.
  • Siracusa V; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygin St. 4, 119991 Moscow, Russia.
  • Iordanskii AL; Department of Chemistry and Physics, Plekhanov Russian University of Economics, Stremyanny Ln 36, 117997 Moscow, Russia.
Polymers (Basel) ; 13(15)2021 Jul 30.
Article en En | MEDLINE | ID: mdl-34372120
Biocompatible glycero (9,10-trioxolane) trioleate (ozonide of oleic acid triglyceride, OTOA) was incorporated into polylactic acid (PLA) fibers by electrospinning and nonwoven PLA mats with 1%, 3% and 5% OTOA content. The morphological, mechanical, thermal and water sorption properties of electrospun PLA mats after the addition of OTOA were studied. A morphological analysis showed that the addition of OTOA increased the average fiber diameter and induced the formation of pores on the fiber surface, leading to an increase in the specific surface area for OTOA-modified PLA fibrous mats. PLA fiber mats with 3% OTOA content were characterized by a highly porous surface morphology, an increased specific surface area and high-water sorption. Differential scanning calorimetry (DSC) was used to analyze the thermal properties of the fibrous PLA mats. The glass transition temperatures of the fibers from the PLA-OTOA composites decreased as the OTOA content increased, which was attributed to the plasticizing effect of OTOA. DSC results showed that OTOA aided the PLA amorphization process, thus reducing the crystallinity of the obtained nonwoven PLA-OTOA materials. An analysis of the mechanical properties showed that the tensile strength of electrospun PLA mats was improved by the addition of OTOA. Additionally, fibrous PLA mats with 3% OTOA content showed increased elasticity compared to the pristine PLA material. The obtained porous PLA electrospun fibers with the optimal 3% OTOA content have the potential for various biomedical applications such as drug delivery and in tissue engineering.
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Rusia

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Rusia