Discovery of Novel HCV NS5B polymerase inhibitor, 2-(3,4-dimethyl-5,5-dioxidobenzo[e]pyrazolo[4,3-c][1,2]thiazin-2(4H)-yl)-N-(2-fluorobenzyl)acetamide via molecular docking and experimental approach.

Khalid, Hina; Shahid, Sana; Tariq, Somayya; Ijaz, Bushra; Ashfaq, Usman Ali; Ahmad, Matloob

Discovery of Novel HCV NS5B polymerase inhibitor, 2-(3,4-dimethyl-5,5-dioxidobenzo[e]pyrazolo[4,3-c][1,2]thiazin-2(4H)-yl)-N-(2-fluorobenzyl)acetamide via molecular docking and experimental approach.

Khalid, Hina; Shahid, Sana; Tariq, Somayya; Ijaz, Bushra; Ashfaq, Usman Ali; Ahmad, Matloob.

Afiliación

Khalid H; Department of Bioinformatics and Biotechnology, Government College University Faisalabad (GCUF), Faisalabad, Pakistan.
Shahid S; Department of Bioinformatics and Biotechnology, Government College University Faisalabad (GCUF), Faisalabad, Pakistan.
Tariq S; Center of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Ijaz B; Center of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Ashfaq UA; Department of Bioinformatics and Biotechnology, Government College University Faisalabad (GCUF), Faisalabad, Pakistan.
Ahmad M; Department of Chemistry, Government College University, Faisalabad, Pakistan.

Clin Exp Pharmacol Physiol ; 48(12): 1653-1661, 2021 12.

Article en En | MEDLINE | ID: mdl-34386985

Asunto(s)

Hepacivirus

Palabras clave

HCV; NS5B; cytotoxicity; docking

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hepacivirus Idioma: En Revista: Clin Exp Pharmacol Physiol Año: 2021 Tipo del documento: Article País de afiliación: Pakistán

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