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Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Schachter, Nathan F; Adams, Jessica R; Skowron, Patryk; Kozma, Katelyn J; Lee, Christian A; Raghuram, Nandini; Yang, Joanna; Loch, Amanda J; Wang, Wei; Kucharczuk, Aaron; Wright, Katherine L; Quintana, Rita M; An, Yeji; Dotzko, Daniel; Gorman, Jennifer L; Wojtal, Daria; Shah, Juhi S; Leon-Gomez, Paul; Pellecchia, Giovanna; Dupuy, Adam J; Perou, Charles M; Ben-Porath, Ittai; Karni, Rotem; Zacksenhaus, Eldad; Woodgett, Jim R; Done, Susan J; Garzia, Livia; Sorana Morrissy, A; Reimand, Jüri; Taylor, Michael D; Egan, Sean E.
Afiliación
  • Schachter NF; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Adams JR; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Skowron P; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Kozma KJ; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Lee CA; Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.
  • Raghuram N; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.
  • Yang J; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Loch AJ; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Wang W; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Kucharczuk A; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.
  • Wright KL; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Quintana RM; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • An Y; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Dotzko D; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Gorman JL; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Wojtal D; Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
  • Shah JS; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Leon-Gomez P; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Pellecchia G; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Dupuy AJ; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Perou CM; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Ben-Porath I; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Karni R; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Zacksenhaus E; Natera, San Francisco, CA, USA.
  • Woodgett JR; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Done SJ; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Garzia L; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Sorana Morrissy A; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
  • Reimand J; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
  • Taylor MD; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
  • Egan SE; Program in Cell Biology, The Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Nat Commun ; 12(1): 5238, 2021 09 02.
Article en En | MEDLINE | ID: mdl-34475389
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Pérdida de Heterocigocidad Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Pérdida de Heterocigocidad Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá