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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.
Porcu, Eleonora; Sadler, Marie C; Lepik, Kaido; Auwerx, Chiara; Wood, Andrew R; Weihs, Antoine; Sleiman, Maroun S Bou; Ribeiro, Diogo M; Bandinelli, Stefania; Tanaka, Toshiko; Nauck, Matthias; Völker, Uwe; Delaneau, Olivier; Metspalu, Andres; Teumer, Alexander; Frayling, Timothy; Santoni, Federico A; Reymond, Alexandre; Kutalik, Zoltán.
Afiliación
  • Porcu E; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland. eleonora.porcu@unil.ch.
  • Sadler MC; Swiss Institute of Bioinformatics, Lausanne, Switzerland. eleonora.porcu@unil.ch.
  • Lepik K; University Center for Primary Care and Public Health, Lausanne, Switzerland. eleonora.porcu@unil.ch.
  • Auwerx C; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Wood AR; University Center for Primary Care and Public Health, Lausanne, Switzerland.
  • Weihs A; Institute of Computer Science, University of Tartu, Tartu, Estonia.
  • Sleiman MSB; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
  • Ribeiro DM; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
  • Bandinelli S; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Tanaka T; University Center for Primary Care and Public Health, Lausanne, Switzerland.
  • Nauck M; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, Devon, UK.
  • Völker U; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
  • Delaneau O; Laboratory of Integrative Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland.
  • Metspalu A; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Teumer A; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
  • Frayling T; Local Health Unit Toscana Centro, Florence, Italy.
  • Santoni FA; Clinical Res Branch, National Institute of Aging, Baltimore, MD, USA.
  • Reymond A; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Kutalik Z; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Nat Commun ; 12(1): 5647, 2021 09 24.
Article en En | MEDLINE | ID: mdl-34561431
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Algoritmos / Predisposición Genética a la Enfermedad / Perfilación de la Expresión Génica / Polimorfismo de Nucleótido Simple / Estudio de Asociación del Genoma Completo / Transcriptoma Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Algoritmos / Predisposición Genética a la Enfermedad / Perfilación de la Expresión Génica / Polimorfismo de Nucleótido Simple / Estudio de Asociación del Genoma Completo / Transcriptoma Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Suiza