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Association of Flow Rate of Prehospital Oxygen Administration and Clinical Outcomes in Severe Traumatic Brain Injury.
Hong, Won Pyo; Hong, Ki Jeong; Shin, Sang Do; Song, Kyoung Jun; Kim, Tae Han; Park, Jeong Ho; Ro, Young Sun; Lee, Seung Chul; Kim, Chu Hyun; Jeong, Joo.
Afiliación
  • Hong WP; Laboratory of Emergency Medical Services, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
  • Hong KJ; 119 EMS Division, The Korean National Fire Agency, Sejong City 30128, Korea.
  • Shin SD; Laboratory of Emergency Medical Services, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
  • Song KJ; Department of Emergency Medicine, College of Medicine, Seoul National University, Seoul 03080, Korea.
  • Kim TH; Department of Emergency Medicine, Seoul National University Hospital, Seoul 03080, Korea.
  • Park JH; Laboratory of Emergency Medical Services, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
  • Ro YS; Department of Emergency Medicine, College of Medicine, Seoul National University, Seoul 03080, Korea.
  • Lee SC; Department of Emergency Medicine, Seoul National University Hospital, Seoul 03080, Korea.
  • Kim CH; Laboratory of Emergency Medical Services, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
  • Jeong J; Department of Emergency Medicine, College of Medicine, Seoul National University, Seoul 03080, Korea.
J Clin Med ; 10(18)2021 Sep 10.
Article en En | MEDLINE | ID: mdl-34575206
The goal of this study was to investigate the association of prehospital oxygen administration flow with clinical outcome in severe traumatic brain injury (TBI) patients. This was a cross-sectional observational study using an emergency medical services-assessed severe trauma database in South Korea. The sample included adult patients with severe blunt TBI without hypoxia who were treated by EMS providers in 2013 and 2015. Main exposure was prehospital oxygen administration flow rate (no oxygen, low-flow 1~5, mid-flow 6~14, high-flow 15 L/min). Primary outcome was in-hospital mortality. A total of 1842 patients with severe TBI were included. The number of patients with no oxygen, low-flow oxygen, mid-flow oxygen, high-flow oxygen was 244, 573, 607, and 418, respectively. Mortality of each group was 34.8%, 32.3%, 39.9%, and 41.1%, respectively. Compared with the no-oxygen group, adjusted odds (95% CI) for mortality in the low-, mid-, and high-flow oxygen groups were 0.86 (0.62-1.20), 1.15 (0.83-1.60), and 1.21 (0.83-1.73), respectively. In the interaction analysis, low-flow oxygen showed lower mortality when prehospital saturation was 94-98% (adjusted odds ratio (AOR): 0.80 (0.67-0.95)) and ≥99% (AOR: 0.69 (0.53-0.91)). High-flow oxygen showed higher mortality when prehospital oxygen saturation was ≥99% (AOR: 1.33 (1.01~1.74)). Prehospital low-flow oxygen administration was associated with lower in-hospital mortality compared with the no-oxygen group. High-flow administration showed higher mortality.
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2021 Tipo del documento: Article