Orexin-A Regulates Follicular Growth, Proliferation, Cell Cycle and Apoptosis in Mouse Primary Granulosa Cells via the AKT/ERK Signaling Pathway.

Safdar, Muhammad; Liang, Aixin; Rajput, Shahid Ali; Abbas, Nasir; Zubair, Muhammad; Shaukat, Aftab; Rehman, Aziz Ur; Jamil, Huma; Guo, Yan; Ullah, Farman; Yang, Liguo

Safdar, Muhammad; Liang, Aixin; Rajput, Shahid Ali; Abbas, Nasir; Zubair, Muhammad; Shaukat, Aftab; Rehman, Aziz Ur; Jamil, Huma; Guo, Yan; Ullah, Farman; Yang, Liguo.

Afiliación

Safdar M; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Liang A; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Rajput SA; Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of Agriculture, Multan 66000, Pakistan.
Abbas N; Department of Animal Nutrition and Feed Sciences, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Zubair M; Department of Animal Breeding & Genetics, PMAS-Arid Agriculture University, Rawalpindi 46300, Pakistan.
Shaukat A; Key Laboratory of Agricultural Microbiology, Education Ministry of China, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Rehman AU; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Jamil H; Department of Pathobiology, University of Veterinary and Animal Sciences, Jhang 35200, Pakistan.
Guo Y; Department of Theriogenology, Faculty of Veterinary Science, University of Agriculture, Faisalabad 38000, Pakistan.
Ullah F; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Yang L; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Education Ministry of China, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.

Molecules ; 26(18)2021 Sep 16.

Article en En | MEDLINE | ID: mdl-34577105

Asunto(s)

Células de la Granulosa/metabolismo; Sistema de Señalización de MAP Quinasas/efectos de los fármacos; Orexinas/fisiología; Folículo Ovárico/citología; Folículo Ovárico/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Animales; Apoptosis/genética; Apoptosis/fisiología; Ciclo Celular/genética; Ciclo Celular/fisiología; Proliferación Celular/genética; Proliferación Celular/fisiología; Regulación hacia Abajo/genética; Femenino; Células de la Granulosa/efectos de los fármacos; Células de la Granulosa/fisiología; Sistema de Señalización de MAP Quinasas/genética; Ratones; Receptores de Orexina/genética; Receptores de Orexina/metabolismo; Orexinas/metabolismo; Folículo Ovárico/efectos de los fármacos; Cultivo Primario de Células

Palabras clave

AKT/ERK1/2 pathway; apoptosis; cell cycle; granulosa cells; orexin; proliferation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas c-akt / Orexinas / Folículo Ovárico / Células de la Granulosa Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China

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