Antibodies to Actinobacillus actinomycetemcomitans in a Korean population.
J Periodontol
; 57(8): 510-5, 1986 Aug.
Article
en En
| MEDLINE
| ID: mdl-3462384
ABSTRACT
Previous studies demonstrated that serum antibodies to Actinobacillus actinomycetemcomitans strain Y4 are significantly elevated in sera from localized juvenile periodontitis (LJP) and postlocalized juvenile periodontitis (P-LJP) patients compared to normal controls in United States populations. This study examined the age of subjects in relation to the antibody levels to A. actinomycetemcomitans in a Korean population. Seven groups were investigated including sera from newborns, infants, children, periodontally normal puberty and adult groups and LJP and P-LJP groups. Antibody levels were determined by an enzyme-linked immunosorbent assay (ELISA) to A. actinomycetemcomitans strain SNUDC 10-1 (serotype C) isolated from a Korean LJP patient. In the healthy non-LJP and non-P-LJP subjects, IgG levels decreased from the newborn group to the 5-month-old group and then gradually increased through the adult group. The IgM levels in these groups continuously increased from birth until a plateau was reached in the 2- to 6-year group. Serum IgA levels to strain SNUDC 10-1 were too low to be measured by this assay.
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Banco de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Actinobacillus
/
Anticuerpos Antibacterianos
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Middle aged
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Periodontol
Año:
1986
Tipo del documento:
Article