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Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex.
Wu, Jiqin; Wang, Haofeng; Liu, Qiaojie; Li, Rui; Gao, Yan; Fang, Xiang; Zhong, Yao; Wang, Meihua; Wang, Quan; Rao, Zihe; Gong, Peng.
Afiliación
  • Wu J; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China.
  • Wang H; School of Life Sciences, Tianjin University, Tianjin 300072, China.
  • Liu Q; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China.
  • Li R; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Gao Y; Laboratory of Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China.
  • Fang X; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Zhong Y; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Wang M; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Wang Q; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: wangq@shanghaitech.edu.cn.
  • Rao Z; Laboratory of Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; National Laboratory of Biom
  • Gong P; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, No. 44 Xiao Hong Shan, Wuhan, Hubei 430071, China; Drug Discovery Center for Infectious Diseases, Nankai University, Tianjin 300350, China. Electronic addre
Cell Rep ; 37(4): 109882, 2021 10 26.
Article en En | MEDLINE | ID: mdl-34653416
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Proteínas Virales / ARN Polimerasa Dependiente del ARN / Adenosina Monofosfato / Alanina / SARS-CoV-2 Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Proteínas Virales / ARN Polimerasa Dependiente del ARN / Adenosina Monofosfato / Alanina / SARS-CoV-2 Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: China