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Multiple strategies for the treatment of invasive breast carcinoma: A comprehensive prospective.
Agarwal, Shivangi; Sau, Samaresh; Iyer, Arun K; Dixit, Anshuman; Kashaw, Sushil K.
Afiliación
  • Agarwal S; Department of Pharmaceutical Sciences, Dr Harisingh Gour University, Sagar, MP, India.
  • Sau S; Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI, USA.
  • Iyer AK; Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Wayne State University, Detroit, MI, USA; Molecular Imaging Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Dixit A; Institute of Life Sciences, Bhubaneswar, Odisha, India.
  • Kashaw SK; Department of Pharmaceutical Sciences, Dr Harisingh Gour University, Sagar, MP, India. Electronic address: sushilkashaw@gmail.com.
Drug Discov Today ; 27(2): 585-611, 2022 02.
Article en En | MEDLINE | ID: mdl-34715356
ABSTRACT
In this review, we emphasize on evolving therapeutic strategies and advances in the treatment of breast cancer (BC). This includes small-molecule inhibitors under preclinical and clinical investigation, phytoconstituents with antiproliferative potential, targeted therapies as antibodies and antibody-drug conjugates (ADCs), vaccines as immunotherapeutic agents and peptides as a novel approach inhibiting the interaction of oncogenic proteins. We provide an update of molecules under different phases of clinical investigation which aid in the identification of loopholes or shortcomings that can be overcomed with future breast cancer research.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inmunoconjugados / Antineoplásicos Tipo de estudio: Observational_studies Límite: Female / Humans Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inmunoconjugados / Antineoplásicos Tipo de estudio: Observational_studies Límite: Female / Humans Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article País de afiliación: India