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Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand.
Siméon, Fabrice G; Lee, Jae-Hoon; Morse, Cheryl L; Stukes, Ian; Zoghbi, Sami S; Manly, Lester S; Liow, Jeih-San; Gladding, Robert L; Dick, Rachel M; Yan, Xuefeng; Taliani, Sabrina; Costa, Barbara; Martini, Claudia; Da Settimo, Federico; Castellano, Sabrina; Innis, Robert B; Pike, Victor W.
Afiliación
  • Siméon FG; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Lee JH; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Morse CL; Department of Nuclear Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 03772, South Korea.
  • Stukes I; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Zoghbi SS; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Manly LS; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Liow JS; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Gladding RL; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Dick RM; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Yan X; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Taliani S; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Costa B; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
  • Martini C; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
  • Da Settimo F; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
  • Castellano S; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
  • Innis RB; Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy.
  • Pike VW; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, United States.
J Med Chem ; 64(22): 16731-16745, 2021 11 25.
Article en En | MEDLINE | ID: mdl-34756026
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de GABA / Radiofármacos / Tomografía de Emisión de Positrones / Flúor Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de GABA / Radiofármacos / Tomografía de Emisión de Positrones / Flúor Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos