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Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.
Sørensen, Gunnar; Rickhag, Mattias; Leo, Damiana; Lycas, Matthew D; Ridderstrøm, Pernille Herrstedt; Weikop, Pia; Lilja, Jamila H; Rifes, Pedro; Herborg, Freja; Woldbye, David; Wörtwein, Gitta; Gainetdinov, Raul R; Fink-Jensen, Anders; Gether, Ulrik.
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  • Sørensen G; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen, Mental Health Center & University of Copenhagen, Copenhagen, Denmark.
  • Rickhag M; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Leo D; Neuroscience and Brain Technologies Department, Italian Institute of Technology, Genoa, Italy.
  • Lycas MD; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ridderstrøm PH; Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen, Mental Health Center & University of Copenhagen, Copenhagen, Denmark.
  • Weikop P; Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen, Mental Health Center & University of Copenhagen, Copenhagen, Denmark.
  • Lilja JH; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Rifes P; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Herborg F; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Woldbye D; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Wörtwein G; Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen, Mental Health Center & University of Copenhagen, Copenhagen, Denmark.
  • Gainetdinov RR; Institute of Translational Biomedicine and Saint-Petersburg University Hospital, Saint-Petersburg State University, Saint-Petersburg, Russia.
  • Fink-Jensen A; Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen, Mental Health Center & University of Copenhagen, Copenhagen, Denmark.
  • Gether U; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: gether@sund.ku.dk.
J Biol Chem ; 297(6): 101361, 2021 12.
Article en En | MEDLINE | ID: mdl-34756883
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Recompensa / Dopamina / Proteínas de Transporte de Dopamina a través de la Membrana Plasmática / Dominios PDZ / Homeostasis / Motivación Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Recompensa / Dopamina / Proteínas de Transporte de Dopamina a través de la Membrana Plasmática / Dominios PDZ / Homeostasis / Motivación Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Dinamarca