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Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb.
Khan, Mona; Yoo, Seung-Jun; Clijsters, Marnick; Backaert, Wout; Vanstapel, Arno; Speleman, Kato; Lietaer, Charlotte; Choi, Sumin; Hether, Tyler D; Marcelis, Lukas; Nam, Andrew; Pan, Liuliu; Reeves, Jason W; Van Bulck, Pauline; Zhou, Hai; Bourgeois, Marc; Debaveye, Yves; De Munter, Paul; Gunst, Jan; Jorissen, Mark; Lagrou, Katrien; Lorent, Natalie; Neyrinck, Arne; Peetermans, Marijke; Thal, Dietmar Rudolf; Vandenbriele, Christophe; Wauters, Joost; Mombaerts, Peter; Van Gerven, Laura.
Afiliación
  • Khan M; Max Planck Research Unit for Neurogenetics, Frankfurt, Germany.
  • Yoo SJ; Max Planck Research Unit for Neurogenetics, Frankfurt, Germany.
  • Clijsters M; Department of Neurosciences, Experimental Otorhinolaryngology, Rhinology Research, KU Leuven, Leuven, Belgium.
  • Backaert W; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Unit, KU Leuven, Leuven, Belgium.
  • Vanstapel A; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
  • Speleman K; Department of Otorhinolaryngology, Head and Neck Surgery, AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium.
  • Lietaer C; Department of Otorhinolaryngology, Head and Neck Surgery, AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium.
  • Choi S; Max Planck Research Unit for Neurogenetics, Frankfurt, Germany.
  • Hether TD; NanoString Technologies Inc., Seattle, WA, USA.
  • Marcelis L; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
  • Nam A; NanoString Technologies Inc., Seattle, WA, USA.
  • Pan L; NanoString Technologies Inc., Seattle, WA, USA.
  • Reeves JW; NanoString Technologies Inc., Seattle, WA, USA.
  • Van Bulck P; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
  • Zhou H; Max Planck Research Unit for Neurogenetics, Frankfurt, Germany.
  • Bourgeois M; Department of Anesthesiology and Intensive Care Medicine, AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium.
  • Debaveye Y; Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine, KU Leuven, Leuven, Belgium.
  • De Munter P; Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Laboratory for Clinical Infectious and Inflammatory Disorders, KU Leuven, Leuven, Belgium.
  • Gunst J; Intensive Care Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine, KU Leuven, Leuven, Belgium.
  • Jorissen M; Department of Neurosciences, Experimental Otorhinolaryngology, Rhinology Research, KU Leuven, Leuven, Belgium; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
  • Lagrou K; Department of Laboratory Medicine and National Reference Centre for Respiratory Pathogens, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, KU Leuven, Leuven, Belgium.
  • Lorent N; Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
  • Neyrinck A; Department of Anesthesia, University Hospitals Leuven, Leuven, Belgium; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
  • Peetermans M; Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Laboratory for Clinical Infectious and Inflammatory Disorders, KU Leuven, Leuven, Belgium.
  • Thal DR; Department of Pathology, University Hospitals Leuven, Leuven, Belgium; Department of Imaging and Pathology, Laboratory of Neuropathology and Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Vandenbriele C; Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
  • Wauters J; Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Laboratory for Clinical Infectious and Inflammatory Disorders, KU Leuven, Leuven, Belgium.
  • Mombaerts P; Max Planck Research Unit for Neurogenetics, Frankfurt, Germany. Electronic address: peter.mombaerts@gen.mpg.de.
  • Van Gerven L; Department of Neurosciences, Experimental Otorhinolaryngology, Rhinology Research, KU Leuven, Leuven, Belgium; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immu
Cell ; 184(24): 5932-5949.e15, 2021 11 24.
Article en En | MEDLINE | ID: mdl-34798069
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bulbo Olfatorio / Autopsia / Mucosa Olfatoria / Mucosa Respiratoria / COVID-19 Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bulbo Olfatorio / Autopsia / Mucosa Olfatoria / Mucosa Respiratoria / COVID-19 Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania